April 2022 – 500 Words A Day

500 Words – Day 034 – What Are Stem Cells? -568-

In 2006, Nobel Prize winners, Kazutoshi Takahashi and Shinya Yamanak, turned the world upside down when they found that skin cells could be reprogrammed and become ‘induced’ pluripotent stem cells. Somatic stem cells are undifferentiated. They are cells found throughout the body that are ready to go at any time. If a name were needed you could call them, “Johnny on the Spot.” They are always ready to be called into service in whatever way the body needs. One purpose they serve is that they replenish any of our senescent(old) cells that have reached the end of their useful life.

Stem cells are located in various locations throughout the body but multiply more readily in the protected environment of our bones marrow, our brain, and our gut. Our three innermost parts. Research shows that stem cells thrive in certain environments and the loss of their power of division and growth occurs when the environment is not favorable. What follows is how stem cells grow and thrive due to several internal and external influences.

1. Caloric Restriction Increases Stem Cell Proliferation

Studies have shown that the number of circulating stem cells in the blood increases with caloric restriction. Additionally, the lifespan of the organs is lengthened. Intermittent fasting or a fasting-mimicking diet is a good way to induce stem cell production and increase the overall functionality of cells. It is these stem cells that are the building materials for our temple.

Chronic inflammation and metabolic problems occur when too many building materials end up in our systems. Studies show that reducing glucose input increases stem cell longevity.

Plain and simple reducing circulating glucose is precisely what the body needs to optimally produce quality stem cells. Foods that are processed or concentrated in any way outside of the body are the biggest culprit.

2. Reduce Triglycerides

The most common causes of high triglycerides are obesity and poorly controlled diabetes. People with high triglycerides are more likely to gain weight, resulting in metabolic syndrome. Additionally, stem cells don’t grow as well in bodies that have high triglycerides.

Some might suggest taking MORE high-quality omega-3 fatty acids to balance out triglycerides and help stem cell growth. I would suggest removing the offending source of the increase returning the body to balance and homeostasis rather than just putting in MORE. Both can be done, but one option is free and I have reservations with the other in that excess is not always better. That doesn’t mean though that there isn’t a place and time where some wisely administered supplements could result in a beneficial end towards whole-body homeostasis.

3. Exercise Boosts Stem Cell Activity

Using our body’s systems results in the proliferation of stem cells by simple means of use. One out, one in. Burn out one stem cell so that the newest one in line can brightly shine. Aerobic exercise in particular aids in this process especially when it comes to stem cells becoming bone instead of fat. When used our muscles activate stem cells as well. These are called mesenchymal stem cells and they are activated by exercise being made available to form new muscle and bone. I would always advise exercising caution in how you go about incorporating any new kind of exercise program. Especially if there are free weights and machines since they end up producing a bit more stress on the overall human creature.

Scribe(author) – Michael J. Loomis | Editor at Chew Digest

500 Words – Day 033 – Reflections on Restoration and Recovery -883 Words-

Death and life are two factors in the same equation. Two sides of the same coin if you will. Disease is not something that happens to us. We are not victims of diseases. We are an organic lifeform that can end up in a state of disease if all of the right environmental conditions are met, combined with long spans of time. As an organic lifeform, perfect health could or should be described as a complete state of ease where everything is systemically working in harmony as designed, completely free of resistance or hindrance.

I prefer to look at life as a spectrum. I do not see death as something that is in front of us but as something that is behind us. The only thing that is truly dead is the time that we spent whether well or poorly spent. We were born into this current existence as sentient lifeforms that will eventually transition away from this current phase of life on Earth. What lay before us is hope and potential. A potential life marked by ease on one end and a life filled with dis-ease on the other end of the spectrum. Pain is my body telling me that I am doing something wrong; suffering results from me not listening to that pain. I’ve learned my lesson, and I am ready to get on with my life.

As I drive around the streets of Los Angeles, I daily see people who likely don’t know that their body is aging much faster than necessary. And some people are just falling apart. I used to be that guy.

June 1, 2022, marks six years since I began a journey of recovery that would be something more than a voyage of grand discovery. On that day, I started my journey toward sober-minded decision-making, which helped me realize that something bigger than me was in charge of what was going on and that my plans were the problem. I had failed some of those around me, but even more so, I had failed my own body, and now it seemed to be failing me. But maybe it wasn’t. Perhaps it was just crying out in pain for some desperately needed attention.

Yet, in my ignorance, my body saw fit to teach me that there is nothing that I can do to improve its functionality. My body already knew the program that I was about to learn. And that if I want it to perform optimally, I need do nothing more than get out of its way, stop interfering, and let it teach me in its ancient ways.

Everything about my body demonstrates less evidence of age, week after week. Day after day, my body confirms that I am continually moving in the right direction. And I can’t imagine that this would continue to happen if I were mistaken. I know that I am unique, as all of us are, but I don’t believe I have any special abilities that every one of you doesn’t also have.

The spontaneous healing of cancer is a phenomenon that can be observed and has been for hundreds and thousands of years. After being the subject of many controversies, it has been accepted as an indisputable fact. Our body can spontaneously heal itself from many stages of disease if it has the right amount and kind of resources, the energy to do the work, and ALL the hydration needed to accomplish the task. And if my body can spontaneously heal from all manner of disease, then I can’t imagine why it shouldn’t be able to recover from any disease state of a lesser nature.

I am a first-hand witness to this in my own life. Provide the body with the proper conditions, nutrients, and sufficient hydration, and it knows nothing other than to find homeostasis and heal whatever keeps you from enjoying a life of ease rather than disease. Just look around at the rest of nature. It does not argue, fuss, or fight. It simply goes with the flow submitting completely to the greater intellect that is creation itself. Nature is never confused and even if we think we can go against nature and its infinitely wise ways we are simply missing the bigger picture. There is no going against nature without removing ourselves from nature which is an impossible feat regardless of courage, skill, or strength. There is no going against nature because even that is part of nature too. You’ll just end up battered, torn, and beaten and nature will still have its way. Our body is nature.

These days I am very fortunate to be looking at a bright future thanks to the human body’s ability to heal itself from the metabolic nightmare I put it through. Alcohol was just the first excess that had to go. Little did I know just how far my body could recover. I have a feeling the life of this body is needed somewhere far off in the future. But for what I don’t yet know?

Biologically, I am a strict determinist. And if there is one thing I see everywhere in nature, it is that biology does not waste energy where there is no potential for the growth of healthy life.

Where is this body taking me? Only time will tell.

RECAST…

In the poetic tapestry of life and death, both elements waltz as twin flames in the theatre of existence. Like dual faces of a single cosmic coin, they teach us of our own fragility and strength. It’s not disease that targets us, as if some cruel game. No, we are but creatures of flesh and bone, and like any living canvas, we might find ourselves marred with time and circumstance.

To me, life doesn’t arc towards death; rather, it flows from it. What’s truly lifeless is not our future but the moments already passed, the echoes of laughter and tears, choices well or ill-made. We emerge from the void, destined to embrace another cosmic journey once we shed this mortal coil. What lies ahead isn’t the gloom of an ending but the brilliance of possibility, a spectrum that spans the blissful serenity of life and the torments of imbalance.

My body, a complex machinery, often signals its needs and discomforts, imploring for care. Yet, sometimes, the soul’s deafness is its own curse. I had to learn, often the hard way, to heed these cries.

Driving through Los Angeles, I am oftentimes haunted by the souls I witness — souls tethered to bodies that seem to age before their time, reflections of the choices they’ve made. I saw myself in them once, a shadow of the man I could be.

More than half a decade ago, the calendar etched a pivotal date. It was the dawn of my personal renaissance, a choice to be sober in thought and action. I recognized the universe’s dance, realizing the chaos was often of my own making. My body bore the scars of my ignorance, yet it remained patient, whispering ancient pearls of wisdom. It wasn’t about conjuring miracles but simply ceasing my interference, allowing nature’s grand design to unveil.

Week by week, as I watched my reflection transform, it was as if time played tricks. My body’s resilience was not a testament to any unique prowess but a universal gift lying dormant in all of us. History is replete with tales of miraculous recoveries, bodies reclaiming their vitality against all odds. If nature could recalibrate itself, why couldn’t the vessel I inhabit?

My journey led me to respect my body’s innate wisdom, to treat it not as a machine but as a living, breathing extension of the universe. Nature doesn’t resist or defy; it gracefully bends, embracing the rhythms set by cosmic laws. Any attempt to defy this dance is but hubris. We are but threads in nature’s vast tapestry.

Today, as I stand at the crossroads of past choices and future possibilities, I am grateful to the miracles of biology. Nature doesn’t indulge in vanity; it invests only where there’s promise. I often wonder where this vessel will lead me next and what destinies lie uncharted.

In the grand ballet of life, if there’s one truth I’ve discerned, it’s that life always seeks growth, expansion, and evolution. And as for where destiny might carry me? That remains a mystery penned by the stars.

500 Words – Day 032 – A Boulder Lifted -1428-

Could my body create a problem big enough that it couldn’t fix it? I am going to suggest the answer is no. Our body doesn’t have the ability to kill itself. Its imperatives are too divine. That would be against its own will and nature.

Or better yet can I even know enough about reality to make the above statement with any surety other than my own self-inflated sense of authority? Maybe not in so much as my knowledge is subject to my own limitations. Yikes. Here we go

The creation that I exist in is infinite, eternal, and unchangeable in its being, wisdom, and power. It is all-sufficient, incomprehensible in its fullness, everywhere in its presence and it is a recording of all things.

The creation that I know exists in and of itself and from itself and is in no way dependent on us for its existence. My creation is not served by me, on the contrary, I am served by it.

The creation that I find in my existence is not unique to me but a stream that is constantly flowing in only one direction without variance. Death is the past, the finite time we call life spent whether productive or not, our most valuable asset, time that cannot be recovered because it is past. That is the realm of death. Now, this present existence, is what is flowing through the river of life, the space-time continuum, what we call our experience is one reason why we are here. To observe and to write it down for future generations to look upon to better understand their present life. Our future is hope. Hope is all we have to look forward to because we cannot do anything about it any more than we can change the past. Of course, we can make plans and even try and execute them, but there is no way of knowing if we will succeed. And hope, if well exercised, allows us the benefits of a sort of salve for the bruises we currently receive and experience as we feel our way, with limited vision, around in this world as we move onward and upward.

As far as I can tell it is futile to even imagine a beginning or an end. I don’t have a light bright enough to shine that far back in time to see what a beginning would look like anyways. My history does not begin and end with me, that is the realm of my creator and its creation. It is the beginning and end; I am just along for the ride and the water is nice in this river of water of life.

If I want to know what is the purpose of this creation of mine I need to look no further than the creation around me. Its purpose and function are everywhere; it knows no different. Our creation, its purpose is life, and life more abundant as each opportunity presents itself. If there is any lack of goodness or purpose in the creation around me it is because I or one like me has interfered in the course of nature; the stream of life(all things).

Purpose, symmetry, and asymmetry…Balance.

Apparently, my creator is also very merciful; compassionate in every way imaginable knowing the unusual amount of distress I once embodied as a creation; even to the ignoring of the continual and even willful missing of the mark. That mark and standard being life, in and of itself.

In its infinite wisdom, my creator placed within its creation provision for the inevitability that marks would be missed and messes well made would need to be cleaned up. Not only is my creator compassionate enough to fix my problems but had enough forethought to plan on them.

The creation I enjoy supplies all of my needs even if I don’t understand that some of what I think I need is not as much of a need, but a desire, or something that possesses me; a possession, which is most likely a liability. It is only when I strip away that which possesses me, that I, with sober-minded clarity, see that my needs are very small and always met, it’s just that I have become gluttonous in my creator’s abundance rather than my own understanding.

This creation is one that does not, by nature, cause distress, but that does not mean that I or one like me within creation cannot, or does not, foment that which is distressing. I know…I am a drama-sapien. It is how, in my own head, I add meaning to my existence. If by chance that added meaning, narrative, or for better lack of a term, drama spills out into the creation around me, somehow mercy was there waiting for me too, with a smile; mop in hand.

This garden I know(my body); is planted within creation, crafted by my creator who is clearly slow to anger. Forgiving of inequity and iniquity alike to maintain a creation free from hindrance always working all things back to the center. Ultimately ready to forgive me for both and more.

The lusts and overindulgences I exhibit in this creation are independent of the creator’s explicit creative act and are inconsistent with my creator’s will(direction/flow). My indiscretions are only eggs on my face and in no way a reflection of my creator.

The creator is not difficult to understand, separated from its creation standing by with disinterest; far from it. And if I ever for a moment begin to think that the river of water of life I find myself in is going to stop, reverse, and flow the other way I should just slap myself. That’s just silly. My creator seems to only know ONE WAY—>

My creation does not and cannot suffer. It only knows life and conservation thereof even through death. My creator is without body, parts, or passions. Without emotion, whether grief, pain, or sorrow; knowing only stability and steadiness of course through its action.

I imagine my creator is nothing I could or should even begin to wrap an image around. So far every god I’ve seen fashioned seems to look an awful lot like the creature rather than the creation. That and I might not like what I see if I actually were able to observe it.

And even if I were able to observe such a creator I imagine it would simply invoke more questions than answers in that the answers were likely never intended to be found, much less searched out.

There is no limit to creation, my creator, or its creative powers. Yet I am limited by what I call time. Limited to such a small sliver of my creators existence that it appears immovable; like a rock. Like a statue frozen in time. Like a man with a swatter, chasing after a fly, wrenching out one grand gesture after another while that fly, from its perspective, is making an epic voyage, like Christopher Columbus, across the vast Sea of Kitchen. I imagine we look much like the Statue of Liberty to that annoying imp of a buzzard.

The power and wisdom of our creator are everywhere all at once in balance whether we see all that is being held in balance; homeostasis.

The power of our creator and creation is a life-giving force that flows from one source; our innermost being and it is simpler than we can imagine because it is precisely the fruit and excesses of our imagination that obscures our access to this creative life-giving force within.

That which is called god for better lack of language is always making provision, continually creating for our future, providing for us everything we need even in our ignorance; gross, slight, or acute. Nature doesn’t just rain on individuals but upon us all, even though it might occasionally seem so as it can appear as though the sun doth smile upon us uniquely at times. That is the joy of creation always working towards the center towards balance and homeostasis.

My creator is always right and good and just; factors of which I have no bearing. A unity in the simplicity of its parts that begins with one that becomes everything else fulfilling all creation as intended from a grand illusion we see as a beginning. We couldn’t create a god if we tried because everything that already exists is god in essence and it is I, the hearty fool to think he can improve on perfection.

It was in me all along…

-Michael J. Loomis

500 Words – Day 031 – Illustration: Circulatory and Lymphatic System

Every once in a while I find a medical illustration that does a really good job visually explaining how something works. This is one of them. Occasionally they inspire me; motivating me to study far beyond my original search for answers.

With this one there are a lot of potential learning and teaching points whether the author or artist intended any additional meaning or potential in their efforts.

I like this one…8). I’ve been intimately aware of my circulatory system as long as I’ve heard my heartbeat. But I didn’t really understand the significance of that extra green part. The lymphatic system. Of course, I had heard of it, but I didn’t fully understand the significance of it and its proper functionality for my well-being. That is until my body decided to teach me a more excellent way of taking care of business. Handling cellular life…8). More on that later.

An adult circulatory system, arteries, and veins, transport about 6,000-7,500 liters or 1,500-2,000 gallons of plasma and its companions, red and white blood cells around the body daily.

The lymphatic system helps maintain fluid balance. It returns excess tissue fluid or blood plasma(same thing; different place) along with proteins from our soft tissues that cannot be returned through the blood vessels.

Blood Plasma = Tissue Fluid = Lymphatic Fluid

The tissue fluid is found in the tissue spaces and cavities, in the tiny spaces surrounding cells, known as the interstitial spaces, which are reached by the smallest blood and lymph capillaries.

Around 90 percent of the plasma that reaches our soft tissues from the arteries and arterial capillaries spills out into our soft tissues. The rest is passed through the veinous side of the capillary beds which then makes its way back to the veins to continue its journey back to the heart. The remaining 10 percent remains in the soft tissues in our interstitium and eventually makes its way back into general circulation through the lymphatic system along with any cellular debris.

Each day, around 2-3 liters find their way back into general circulation via the lymphatic system when it is functioning optimally. This fluid includes waste proteins that are too large to be transported via the blood vessels. As that process is taking place these proteins are continually denatured along the way until they reenter general circulation at the end of their journey just above our heart where it begins the journey all over again.

If this system were to completely fail to function properly the toxic burden on our bodies would be too great and we would die within a day. Without this third leg of our circulatory system draining its fluids excess waste or cellular debris, our soft tissues would swell. Blood volume would also decrease because that fluid is our blood plasma, just outside the arteries and veins and blood pressure would increase until the skin, kidneys, liver, and lungs become overburdened resulting in eventual and possibly acute failure.